Goes Well With
Nutritionally supporting vibrant mental health can be difficult through food alone. The modern diet might not provide you with all of the nutrients that your brain needs, and if you want brain performance over and above "normal," you might have to supplement.
Alpha GPC is a great brain supplement for both shifting the brain into top gear and also to enhance some brain powering compounds you might already be taking.
What is it?
Alpha GPC (L-Alpha Glycerylphosphorylcholine) is a choline compound that is found in the human body, milk, soy, and some other plants. It is a phospholipid most notable for the low energy cost to transform Alpha GPC into an effective brain building compound.
Due to the water solubility of Alpha GPC and its quick absorption, this form of choline is quickly becoming a popular addition to many nootropic stacks, and it is being used as a nootropic in its own right.
Users most often take Alpha GPC for the improvement of general cognition, memory, thinking, and learning. Alpha GPC has been repeatedly shown to increase attention and certain aspects of memory.  
Not only does Alpha GPC provide choline, it bonds with the omega-3 fatty acid docosahexaenoic acid (DHA) through an enzyme process that builds new membranes that promote nerve cell expansion.
This nerve expanding property of Alpha GPC is not its only claim to fame, because Alpha GPC also supports high choline levels. This helps in the creation of acetylcholine which is one of the most important neurotransmitters when it comes to thinking, memory, and learning.
High acetylcholine levels created by Alpha GPC supplementation can also benefit people who are seeking to enhance brain-muscle integration. Alpha GPC has also shown to improve brain functioning in young people.
Finding the right Alpha GPA dosage can be a little tricky. It is always best to start low, but if you are using Alpha GPC powder to support a racetam regimen, you might need a little bit more than an individual using Alpha GPC powder for its own nootropic properties. 300 mg is about as low as you can start, and some people take as much as 1200 mg a day.
- Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine.
- Kidd, Parris M. GPC (ClyceroPhosphoCholine) Mind-Body Power for Active Living and Healthy Aging. First ed. N.p.: TotalHealth, 2007.
- Kidd, Parris M. "Neurodegeneration From Mitochondrial Insufficiency: Nutrients, Stem Cells, Growth Factors, And Prospects For Brain Rebuilding Using Integrative Management." Alternative Medicine Review 10.4 (2005): 268-293. Academic Search Elite. Web. 8 Sept. 2012.
- Phospholipids: Versatile Nutraceuticals for Functional Foods [pdf]
- Choline and choline esters in human and rat milk and in infant formulas.
This is a great cognitive and memory enhancer and worthy of anyone shooting for that ultimate NZT stack.
The second batch I received was totally different, which is already a pretty bad sign in a supplement. Not creamy, but instead sandy feeling, not completely water soluble. It has a bad taste, and I have to take higher doses to notice the effects. The COA says it all, now that I've finally looked at it closely (my bad for not looking in the first place). The product claims to be "pure bulk powder", but "pure" is not quite the right word for a product that is 52% Alpha GPC, and 48% other (mostly dicalcium phosphate dihydrate, which is a calcium supplement mostly used in processed/pet foods). There's also 0.5-1.5% silicon dioxide...yep...the product is about 1% sand. Adding calcium is probably not hazardous (though theoretically does increase the possibility of excitotoxicity from some ampakines, like aniracetam or sunifiram), but it's doubling the shipping weight and adding no value. Also, the supplement information label is still incorrect after several months of my mentioning that the label says that taking 500mg of the product will provide 150mg of alpha GPC (it should say ~250mg of alpha GPC).
I generally like this site, but this particular product is not up to the standard of quality I see elsewhere. Please fix it. Silicon Dioxide and Dicalcium Phosphate are not water soluble like Alpha GPC, so you or your supplier should easily be able to purify this and truly offer "pure bulk powder". Get your supplier to do it, so you can halve your shipping costs?...
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new product. Do not take this product if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues.
Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a product, since there are many unaccounted variables, which fall outside the scope of the studies.
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